maternal serum levels of transforming growth factor ß1 (tgf-ß1) in normal and preeclamptic pregnancies

Maternal Serum Levels of Transforming Growth Factor ß1 (TGF-ß1) in Normal and Preeclamptic Pregnancies

Background: Successful pregnancy in allopregnant women depends upon the control of graft rejection mechanisms. It has been suggested that some immunosuppressive cytokines contribute to successful pregnancy and transplantation. Transforming growth factor beta (TGF-   β) exhibits potent immunoregulatory and anti-inflammatory properties which might prolong graft survival. Recent studies suggest a ...

Lysyl Oxidase Regulates Transforming Growth Factor-ß1 Function in Bone

Comparison of thyroid hormone levels between normal and preeclamptic pregnancies

 Background: To investigate thyroid function in preeclamptic patients in comparison with normal pregnant women. Methods: In this analytical cross-sectional study free Thyroxine (T4), and Thyroid Stimulating Hormone (TSH) levels were measured in 100 preeclamptic patients and were compared with Free T4 and TSH levels in 101 normal pregnant women in their third trimester of pregnancy. Patient...

Relationship between serum transforming growth factor ß1 and liver collagen content in rats treated with carbon tetrachloride.

CONTEXT Transforming Growth Factor ß1 (TGFß1) plays a fundamental role in fibrogenesis, although its importance as a biomarker of liver disease is still matter of debate. OBJECTIVE Quantify serum TGFß1 and its association to liver collagen content in rats exposed to Carbon Tetrachloride (CCl4). METHODS Rats were submitted to a fibrosis model using CCl4 and sacrificed after 6, 10, 12 and 16 ...

Shear-Induced Activation of Latent TGF-ß1 in Synovial Fluid

INTRODUCTION: Transforming growth factor beta (TGF-β) is a ubiquitous multifunctional cytokine that modulates the growth, differentiation, and proliferation of most cell types. In cartilage, TGF-β has been shown to directly influence DNA and protein synthesis [1,2]. Additionally, TGF-β is believed to be present in synovial fluid [3,4] as well as released by chondrocytes as an autocrine regulato...

Serum Level of High Sensitive C-Reactive Protein in Normal and Preeclamptic Pregnancies

Background and Objective: The aim of this study was to determine the level of plasma high sensitive c-reactive protein (hs-CRP) in preeclampsia and to compare hs-CRP levels between normal pregnant women, mild preeclamptic, and severe preeclamptic women. Materials and Methods: Serum hs-CRP levels were inv...